Observations on the Treatment of 25 Cases of Kala-Azar with Stibatin (Sodium Antimony Gluconate) *Being a paper read at the Annual General Meeting of the Surma Valley and Chittagong Division of the British Medical Association held at the Lungla Club on 26th January, 1946. †The paper condensed by the editor.
نویسنده
چکیده
severe toxic reactions and, as such, small children, corpulent subjects and patients suffering from general anasarca, not an uncommon condition associated with kala-azar, could not be treated with urea stibamine. At the Annual General Meeting of the Assam and Northern Bengal Branch of the British Medical Association that was held in Shillong in November 1943, Shortt read an interesting paper dealing with the history of researches on kala-azar in Assam and in the discussions that followed Burke and Chakravarty (1944) of Mangaldai Medical Association described the most encouraging results they had obtained with stibatin which, they said, was remarkably non-toxic and could be administered both by the intramuscular and the intravenous routes.
منابع مشابه
The Treatment of Kala-Azar with Sodium Antimony Gluconate (Stibatin). Further Observations on the Treatment of Thirty-Two Cases
couraging results, it was decided to a further extensive trial with this drug in certain hyperendemic kala-azar areas in the tea districts of Mangaldai, as an anti-kala-azar drug of such promising quality was indispensable, especially when, due to present war-time conditions, other pentavalent antimony compounds of proved value, e.g. solustibosan, neostibosan, etc., suitable for mass administra...
متن کاملA Preliminary Note on the Treatment of 21 Cases of Kala-Azar with Sodium Antimony Gluconate. (With Special Reference to Its Suitability for Mass Administration on Tea Estates)
Introduction.?The senior writer, Burke (1943), made an appeal for an efficient successor to neostibosan (Bayer), this, preferably, to be a British product. What seems to be an almost perfect answer to that appeal?and indeed a British product?is the preparation stibatin (Glaxo Laboratories), or sodium antimony gluconate (antimony v-hexonate), a crystal-clear sterile solution containing 20 mg. of...
متن کاملThe Treatment of Kala-Azar with Sodium Antimony-V-Gluconate: Preliminary Observations *The work reported in this paper was undertaken under the Endowment Fund of the Calcutta School of Tropical Medicine, aided by a grant from the Indian Research Fund Association.
A pentavalent antimony compound (Sdt. 561, solustibosan, antimony-v-hexonate, containing 20 mg. of antimony per c.cm. of solution) , that made a stable solution and could be given intramuscularly, was first introduced b) Prof. H. Schmidt, the pioneer worker on pent*1' valent antimony compounds. Kikuth and Schmidt (1938) found that this compound possessed a marked curative action in the le*,' ma...
متن کاملبیماریابی کالا آزار با استفاده از روش آگلوتیناسیون مستقیم
Visceral leishmaniasis (VL) has been found as an endemic disease in some areas in northwest and south parts of Iran during recent two decades. The species of the Leishmania has been characterized as L.infantum and the main sources of human infection in the endemic areas is dog. The majority of kala-azar cases are found among children in the age group of 1-4 years. As the delay in diagnosis and ...
متن کاملSodium Antimonyv Gluconate in the Treatment of Indian Kala-Azar
The preliminary results of treatment of 50 cases of kala-azar and 2 cases of post-kala-azar dermal leishmaniasis were reported by the writers (Sen Gupta and Chakravarty, 1945) last year. Of the 50 cases of kala-azar treated, two died during treatment and 48 were discharged as clinically cured. The immediate results of this trial were quite satisfactory, the immediate cure rate being about 96 pe...
متن کامل